Fraud in Medical Research: Understanding the Carlisle Approach

Fraud in Medical Research: Understanding the Carlisle Approach

A "bombshell" paper appearing in the journal Anesthaesia uses a simple statistical test to suggest that a significant proportion of medical studies - some from our most prestigious journals - may be fabrications. But the story is not a clear cut as it seems. For the video version, click here.

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Propensity Scores: Observational Data and Wishful Thinking

Propensity Scores: Observational Data and Wishful Thinking

Propensity score methods attempt to make observational data look like a randomized trial. But there are some big limitations that need to be considered before we jump on the bandwagon. For the video version, click here.

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Antidepressants in Mothers, Autism in Children: The Data

Antidepressants in Mothers, Autism in Children: The Data

This week, three studies were published that explore a potential link between antidepressant use during pregnancy and autism in offspring. In this deep dive, we explore the nuances of the data to determine just how worried moms-to-be should be. For the video version, click here.

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Bayes Factors, Miracle Cures, and the FDA

Bayes Factors, Miracle Cures, and the FDA

A study appearing in Plos One suggests that a statistic called the Bayes Factor will keep the FDA from approving bad drugs. It won't, but rigorous defense of their regulatory powers will. For the video version, click here.

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What Percent of Medical Studies Are Wrong?

What Percent of Medical Studies Are Wrong?

We know that some medical studies are wrong.  But how many? The number might be more than you think.  And it turns out that a quarter, a street magician, and an 18th century minister might be the key to figuring it out. For the video version, click here.

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One Weird Trick that Would Get Epipen Fully Covered By Insurance

One Weird Trick that Would Get Epipen Fully Covered By Insurance

Mylan pharmaceuticals is lobbying the United States Preventive Services Task Force to label Epipen as a "preventive" medication, which would effectively transfer the exorbitant cost from individuals to insurance companies. This is not the right strategy, folks. For the video version, click here.

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